NVP-TAE 226 [761437-28-9]

MedChem Express

NVP-TAE 226 [761437-28-9]

10

761437-28-9

Research Use Only

99.77

C23H25ClN6O3

468.94

NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively[1][2].

O=C(C1=C(C=CC=C1)NC2=NC(NC3=C(C=C(C=C3)N4CCOCC4)OC)=NC=C2Cl)NC

-20°C,2°C to 8°C

12352200