NVR3-778 hydrate [2093094-04-1]

TargetMol Chemicals

NVR3-778 hydrate [2093094-04-1]

72

Research Use Only

NVR3-778 hydrate

C18H18F4N2O5S

450.4

NVR 3-778 is the first capsid assembly modulator (CAM) that has demonstrated antiviral activity in hepatitis B virus (HBV)-infected patients. NVR 3-778 inhibited the generation of infectious HBV DNA-containing virus particles with a mean antiviral 50% effective concentration (EC50) of 0.40 microM in HepG2.2.15 cells. The antiviral profile of NVR 3-778 indicates pan-genotypic antiviral activity and a lack of cross-resistance with nucleos(t)ide inhibitors of HBV replication.

3 years

O.OC1CCN(CC1)S(=O)(=O)c1cc(ccc1F)C(=O)Nc1cc(F)c(F)c(F)c1

-20°C

12352200