NW-1689 [405-85-6]

MedChem Express

NW-1689 [405-85-6]

5

405-85-6

Research Use Only

C14H11FO3

246.23

NW-1689 is a process-related impurity of safinamide mesilate (SAFM). SAFM is a drug used to treat Parkinsons disease (PD). It is a highly selective and reversible inhibitor of monoamine oxidase-B (MAO-B) and also blocks sodium channels and N-type calcium channels. These effects of SAFM help reduce the breakdown of dopamine and inhibit the release of glutamate. NW-1689 has a similar chemical structure to SAFM and has some similar pharmacological effects as SAFM, and can be used in Parkinsons disease research[1].

C1=CC(=CC(=C1)F)COC2=CC=C(C=C2)C(=O)O

12352200