NX-2127

AbMole BioScience

NX-2127

9

2416131-46-7

Chemical

Research Use Only

C39H45N9O5

719.83

NX-2127 is an orally active, potent BTK inhibitor that induces degradation of mutant BTKC481S in cells, as well as inhibits the proliferation of BTKC481S mutant TMD8 cells. In addition, NX-2127 stimulates T cell activation and increases IL-2 production in primary human T cells.

NC(=O)C1=NC=C(N=C1NC2=CC=C(C=C2)C3CCN(CC3)CC4CCN(C4)C5=CC=C6C(=O)N(C7CCC(=O)NC7=O)C(=O)C6=C5)N8CCCCC8

4°C, protect from light

12352200