O-Carboranylphenoxyacetanilide [2260545-92-2]

TargetMol Chemicals

O-Carboranylphenoxyacetanilide [2260545-92-2]

9

Research Use Only

C16H24B11NO5

429.29

O-Carboranylphenoxyacetanilide is an HIF-1alpha inhibitor that suppresses the activation of HIF-1alpha. It inhibits the transcriptional activity of HIF in HeLa cells (IC50: 0.74 microM) and also suppresses the molecular chaperone activity of HSP60 as well as the HSP60 ATPase activity.

O=C(NC1=CC(=CC=C1O)B(O)O)COC2=CC=C(C=C2)C3456[BH]789[BH]%10%11%12[BH]%13%149[BH]%10%15%16[BH]%11%17%18[BH]%1276[BH]%17%195[BH]%20%214[BH]%13%15([BH]%148%203)[CH]%16%18%19%21

-20°C

12352200