O-Desmethyl Brinzolamide hydrochloride [2967475-56-3]

TargetMol Chemicals

O-Desmethyl Brinzolamide hydrochloride [2967475-56-3]

16

C11H20ClN3O5S3

405.94

O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].

O=S1(=O)C2=C([C@@H](NCC)CN1CCCO)C=C(S(N)(=O)=O)S2.Cl

-20°C

12352200