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O-Desmethyl gefitinib

ORB1741541
Biorbyt
CAS Number847949-49-9
Product group Chemicals
Molecular Weight432.88
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Overview

  • Supplier
    Biorbyt
  • Product Name
    O-Desmethyl gefitinib [847949-49-9]
  • Delivery Days Customer
    10
  • CAS Number
    847949-49-9
  • Certification
    Research Use Only
  • Molecular Formula
    C21H22ClFN4O3
  • Molecular Weight
    432.88
  • Scientific Description
    O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human plasma, O-Desmethyl gefitinib is an active metabolite of Gefitinib. The formation of O-desmethyl gefitinib is dependent on the CYP2D6 activity.
  • SMILES
    Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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