O6-Benzylguanine [19916-73-5]
HY-W002585
CAS Number19916-73-5
Product group Chemicals
Estimated Purity99.97
Molecular Weight241.25
Overview
- SupplierMedChem Express
- Product NameO6-Benzylguanine [19916-73-5]
- Delivery Days Customer9
- CAS Number19916-73-5
- CertificationResearch Use Only
- Estimated Purity99.97
- Molecular FormulaC12H11N5O
- Molecular Weight241.25
- Scientific DescriptionO6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity[1][2].
- SMILESNC(N=C1OCC2=CC=CC=C2)=NC3=C1NC=N3
- Storage InstructionRT
- UNSPSC12352200
MSDS
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