Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Mouse heart tissue, Primary antibody: CSB-PA780177(OAS2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds

OAS2 Antibody

Name: OAS2 Antibody
SKU: CSB-PA780177_C90
Availability: BackOrder

CSB-PA780177

ApplicationsWestern Blot, ELISA

Product group Antibodies

ReactivityHuman, Mouse

TargetOAS2

Overview

Supplier
Cusabio
Product Name
OAS2 Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID4939
Target name
OAS2
Target description
2'-5'-oligoadenylate synthetase 2
Target synonyms
(2'-5')oligo(A) synthetase 2; 2-5A synthase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; p69 OAS / p71 OAS
Host
Rabbit
Isotype
IgG
Protein IDP29728
Protein Name
2'-5'-oligoadenylate synthase 2
Scientific Description
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2-specific nucleotidyl transfer reactions to synthesize 2,5-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

OAS2 Antibody

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Overview

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