OAS2 Antibody

Cusabio

OAS2 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

OAS2

2'-5'-oligoadenylate synthetase 2

2'-5'-oligoadenylate synthase 2, (2'-5')oligo(A) synthetase 2, 2'-5'-oligoadenylate synthetase 2, 69/71kDa, 2-5A synthase 2, p69 OAS / p71 OAS

Rabbit

IgG

2'-5'-oligoadenylate synthase 2

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2-specific nucleotidyl transfer reactions to synthesize 2,5-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Human, Mouse

-20°C or -80°C

41116161