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OB 24 hydrochloride [939825-12-4]

OB 24 hydrochloride [939825-12-4]

T41175
TargetMol Chemicals
CAS Number939825-12-4
Product group Chemicals
Molecular Weight373.68
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    OB 24 hydrochloride [939825-12-4]
  • Delivery Days Customer
    44
  • CAS Number
    939825-12-4
  • Certification
    Research Use Only
  • Chemical Name
    OB 24 hydrochloride
  • Molecular Formula
    C15H18BrClN2O2
  • Molecular Weight
    373.68
  • Scientific Description
    OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 microM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA). Inhibits cell proliferationin vitroand PCA tumor growth and lymph node/lung metastasesin vivo. Synergizes with Taxol.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Brc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200