ODN 2216 [332437-00-0]

MedChem Express

ODN 2216 [332437-00-0]

10

332437-00-0

Research Use Only

97.92

6432.00

ODN 2216 is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. ODN 2216 induces high amounts of IFN-alpha and IFN-beta. ODN 2216 induces IFN-alpha by pDC (plasmacytoid DC) and IL-12 (p40) production by DC (dendritic cells). ODN 2216 stimulates IFN-gamma production in peripheral blood mononuclear cells (PBMC), which is indirect and mediated by IFN-alpha/beta. ODN 2216 can activate NK cells and promote IFN-gamma production of TCR-triggered CD4+ T cells[1][2][3][4][5].

[DNA, d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G)]

-20°C

41115811