OGDH antibody [C2C3], C-term
GTX105124
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetOGDH
Overview
- SupplierGeneTex
- Product NameOGDH antibody [C2C3], C-term
- Delivery Days Customer9
- Antibody SpecificityBased on sequence homology, this antibody may cross react with OGDHL protein.
- Application Supplier NoteWB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID4967
- Target nameOGDH
- Target descriptionoxoglutarate dehydrogenase
- Target synonyms2-oxoglutarate dehydrogenase complex component E1; 2-oxoglutarate dehydrogenase, mitochondrial; AKGDH; E1k; KGD1; OGDC; OGDC-E1; OGDH2; oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide); oxoglutarate decarboxylase; oxoglutarate dehydrogenase (succinyl-transferring); testicular tissue protein Li 131
- HostRabbit
- IsotypeIgG
- Protein IDQ02218
- Protein Name2-oxoglutarate dehydrogenase, mitochondrial
- Scientific DescriptionThis gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- alpha-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis. Atlante S et al., 2018 Jul 9, Cell Death DisRead more
- Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the alpha-Ketoglutarate Signaling Pathway. Tseng CW et al., 2018 Jun 1, Cancer ResRead more