Ogerin

MedChem Express

Ogerin [1309198-71-7]

10

1309198-71-7

Research Use Only

99.58

C17H17N5O

307.35

Ogerin is a selective GPR68 positive aliasing modulator (PAM) ( pEC 50 =6.83) with a moderate antagonistic effect on A 2A ( K i =220 nM). Ogerin inhibits the fear conditioning reflex in mice and also inhibits TGF-beta -induced myofibroblast differentiation of fibroblasts from multiple organ systems. Ogerin can be used in the studies of fibrotic diseases and neurological disorders [1] [2] .

OCC1=C(C2=NC(N)=NC(NCC3=CC=CC=C3)=N2)C=CC=C1

-20°C,2°C to 8°C

12352200