Olanzapine

MedChem Express

Olanzapine [132539-06-1]

10

132539-06-1

Research Use Only

99.37

C17H20N4S

312.442

Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 ( K i =7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 ( K i =11 to 31 nM), muscarinic M1-5 ( K i =1.9-25 nM), and adrenergic alpha1 receptor ( K i =19 nM). Olanzapine is an atypical antipsychotic [1] [2] .

CC1=CC(C(N2CCN(C)CC2)=N3)=C(S1)NC4=C3C=CC=C4

2°C to 8°C

12352200