Olanzapine-d8

MedChem Express

Olanzapine-d8 [1093380-13-2]

5

1093380-13-2

Research Use Only

C17H12D8N4S

320.48

Olanzapine-d8 is a deuterated labeled Olanzapine [1] . Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 ( K i =7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 ( K i =11 to 31 nM), muscarinic M1-5 ( K i =1.9-25 nM), and adrenergic alpha1 receptor ( K i =19 nM). Olanzapine is an atypical antipsychotic [2] [3] .

CC1=CC2=C(S1)NC3=CC=CC=C3N=C2N4C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C4([2H])[2H])C

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