Olaparib

MedChem Express

Olaparib [763113-22-0]

10

763113-22-0

Research Use Only

99.98

C24H23FN4O3

434.46

Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC 50 s of 5 and 1 nM for PARP1 and PARP2 , respectively. Olaparib is an autophagy and mitophagy activator [1] [2] [3] [4] .

O=C(C1=CC(CC(C2=C3C=CC=C2)=NNC3=O)=CC=C1F)N4CCN(C(C5CC5)=O)CC4

-20°C,2°C to 8°C

12352200