Olaparib-d8

MedChem Express

Olaparib-d8

10

Research Use Only

99.57

C24H15D8FN4O3

442.51

Olaparib-d 8 (AZD2281-d 8 ) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC 50 s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator [1] [2] [3] [4] .

O=C1NN=C(CC2=CC=C(F)C(C(N3C([2H])([2H])C([2H])([2H])N(C(C4CC4)=O)C([2H])([2H])C3([2H])[2H])=O)=C2)C5=C1C=CC=C5

-20°C,2°C to 8°C

12352200