Olcegepant

MedChem Express

Olcegepant [204697-65-4]

10

204697-65-4

99.83

C38H47Br2N9O5

869.65

Olcegepant (BIBN-4096) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC 50 of 0.03 nM and K i of 14.4 pM for human CGRP [1] [2] .

O=C1N(CC2=C(N1)C=CC=C2)C3CCN(C(N[C@@H](C(N[C@H](C(N4CCN(C5=CC=NC=C5)CC4)=O)CCCCN)=O)CC6=CC(Br)=C(C(Br)=C6)O)=O)CC3

-20°C,2°C to 8°C

12352200