Oleyl Anilide [5429-85-6]

TargetMol Chemicals

Oleyl Anilide [5429-85-6]

10

5429-85-6

Research Use Only

Oleyl Anilide

C24H39NO

357.57

AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransferase (ACAT) with an IC50 of 26 microM. OA and the related glyceride dioleoyl phenylamino propane 1,2-diol have been linked to a syndrome of eosinophilia, excessive T-cell activation, and elevated interleukin-4 (IL-4), soluble IL-2R, and IL-5. The clinical consequences are an acute pulmonary inflammatory reaction followed by chronic neuropathy, myalgia, and autoimmune connective tissue disease, generally referred to as toxic oil syndrome (TOS). Aniline-denatured cooking oil is a source of OA associated with TOS.

3 years

N(C(CCCCCCC/C=C\CCCCCCCC)=O)C1=CC=CC=C1

-20°C

12352200