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Olodanrigan [1316755-16-4]

Olodanrigan [1316755-16-4]

T4431
TargetMol Chemicals
CAS Number1316755-16-4
DownloadMSDS
Product group Chemicals
Estimated Purity0.9413
Molecular Weight507.58
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Olodanrigan [1316755-16-4]
  • Delivery Days Customer
    9
  • CAS Number
    1316755-16-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Olodanrigan
  • Estimated Purity
    0.9413
  • Molecular Formula
    C32H29NO5
  • Molecular Weight
    507.58
  • Scientific Description
    Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. EMA401 blocks p38, p42/p44 mitogen-activated protein kinase (MAPK) activation, neurite outgrowth in adult rat DRG neurons, and sensitization of adult rat and human DRG neurons induced by AngII. It inhibits capsaicin responses in cultured hDRG neurons.
  • Shelf life instruction
    3 years
  • SMILES
    COc1ccc2CN([C@@H](Cc2c1OCc1ccccc1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200