Olomoucine

MedChem Express

Olomoucine [101622-51-9]

5

101622-51-9

Research Use Only

99.87

C15H18N6O

298.34

Olomoucine is an ATP competitive inhibitor of CDK s. Olomoucine is a purine (HY-34431) derivative and inhibits CDC2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E (both IC 50 =7 microM), CDK/p35 kinase ( IC 50 =3 microM) and ERK1/p44 MAP kinase ( IC 50 =25 microM) [1] [2] . Olomoucine regulates cell cycle and shows anti-melanin tumor activity [3] [4] .

CN1C=NC2=C(NCC3=CC=CC=C3)N=C(NCCO)N=C12

-20°C,2°C to 8°C

12352200