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Olomoucine [101622-51-9]

HY-W011428
MedChem Express
CAS Number101622-51-9
Product group Chemicals
Estimated Purity99.88
Molecular Weight298.34
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Olomoucine [101622-51-9]
  • Delivery Days Customer
    5
  • CAS Number
    101622-51-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.88
  • Hazard Information
    h315, h319, h335
  • Molecular Formula
    C15H18N6O
  • Molecular Weight
    298.34
  • Scientific Description
    Olomoucine is an ATP competitive inhibitor of CDKs. Olomoucine is a purine (HY-34431) derivative and inhibits CDC2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E (both IC50=7 microM), CDK/p35 kinase (IC50=3 microM) and ERK1/p44 MAP kinase (IC50=25 microM)[1][2]. Olomoucine regulates cell cycle and shows anti-melanin tumor activity[3][4].
  • SMILES
    CN1C=NC2=C(NCC3=CC=CC=C3)N=C(NCCO)N=C12
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200