Olorofim [1928707-56-5]

TargetMol Chemicals

Olorofim [1928707-56-5]

4

1928707-56-5

Chemical

Research Use Only

Olorofim

99.28%

C28H27FN6O2

498.55

Olorofim (F-901318) is a novel selective antifungal compound targeting pyrimidine biosynthesis in mycobacteria, with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM), but little inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against a variety of pathogenic filamentous and dimorphic fungi, such as Penicillium spp, P. dermatitidis spp and Fusarium spp.

3 years

C(C(NC1=CC=C(C=C1)N2CCN(CC2)C=3N=CC(F)=CN3)=O)(=O)C4=C(C=C(C)N4C)C5=CC=CC=C5

-20°C

12352200