OLR1 / LOX-1 antibody [23C11]

GeneTex

OLR1 / LOX-1 antibody [23C11]

9

The monoclonal antibody 23C11 recognizes oxidized low-density lipoprotein receptor-1 (LOX-1). Monoclonal antibody 23C11 neutralizes LOX-1 and inhibits Hsp70 binding to dendritic cells and Hsp70-induced antigen cross-presentation. In vivo, targeting LOX-1

FACS: 10 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking

Research Use Only

Monoclonal

23C11

100 ug/ml

Unconjugated

OLR1

oxidized low density lipoprotein receptor 1

CLEC8A; C-type lectin domain family 8 member A; hLOX-1; lectin-type oxidized LDL receptor 1; LOX1; LOXIN; ox LDL receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low-density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1, soluble form; SCARE1; scavenger receptor class E, member 1; SLOX1

Mouse

IgG1

Oxidized low-density lipoprotein receptor 1

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimers disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Human, Mouse

2°C to 8°C

12352203