ON1231320
HY-100789
CAS Number1312471-39-8
Product group Chemicals
Estimated Purity99.24
Molecular Weight467.45
Overview
- SupplierMedChem Express
- Product NameON1231320 [1312471-39-8]
- Delivery Days Customer10
- CAS Number1312471-39-8
- Estimated Purity99.24
- Molecular FormulaC22H15F2N5O3S
- Molecular Weight467.45
- Scientific DescriptionON1231320 is a highly specific polo like kinase 2 (PLK2) inhibitor with an IC 50 of 0.31 microM. ON1231320 blocks tumor cell cycle progression in the G2/M phase in mitosis, causing apoptotic cell death. ON1231320, an arylsulfonyl pyrido-pyrimidinone, has antitumor activity [1] [2] .
- SMILESO=C1C(S(=O)(C2=CC=C(F)C=C2F)=O)=CC3=CN=C(NC4=CC5=C(NC=C5)C=C4)N=C3N1C
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200