ON1231320

MedChem Express

ON1231320 [1312471-39-8]

10

1312471-39-8

Research Use Only

99.24

C22H15F2N5O3S

467.45

ON1231320 is a highly specific polo like kinase 2 (PLK2) inhibitor with an IC 50 of 0.31 microM. ON1231320 blocks tumor cell cycle progression in the G2/M phase in mitosis, causing apoptotic cell death. ON1231320, an arylsulfonyl pyrido-pyrimidinone, has antitumor activity [1] [2] .

O=C1C(S(=O)(C2=CC=C(F)C=C2F)=O)=CC3=CN=C(NC4=CC5=C(NC=C5)C=C4)N=C3N1C

-20°C,2°C to 8°C

12352200