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ON1231320

HY-100789
MedChem Express
CAS Number1312471-39-8
Product group Chemicals
Estimated Purity99.24
Molecular Weight467.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ON1231320 [1312471-39-8]
  • Delivery Days Customer
    10
  • CAS Number
    1312471-39-8
  • Estimated Purity
    99.24
  • Molecular Formula
    C22H15F2N5O3S
  • Molecular Weight
    467.45
  • Scientific Description
    ON1231320 is a highly specific polo like kinase 2 (PLK2) inhibitor with an IC 50 of 0.31 microM. ON1231320 blocks tumor cell cycle progression in the G2/M phase in mitosis, causing apoptotic cell death. ON1231320, an arylsulfonyl pyrido-pyrimidinone, has antitumor activity [1] [2] .
  • SMILES
    O=C1C(S(=O)(C2=CC=C(F)C=C2F)=O)=CC3=CN=C(NC4=CC5=C(NC=C5)C=C4)N=C3N1C
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200