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Onalespib [912999-49-6]

Onalespib [912999-49-6]

T6284
TargetMol Chemicals
CAS Number912999-49-6
DownloadMSDS
Product group Chemicals
Estimated Purity99.82%
Molecular Weight409.52
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Onalespib [912999-49-6]
  • Delivery Days Customer
    9
  • CAS Number
    912999-49-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Onalespib
  • Estimated Purity
    99.82%
  • Molecular Formula
    C24H31N3O3
  • Molecular Weight
    409.52
  • Scientific Description
    Onalespib (AT13387) is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. Hsp90, a chaperone protein upregulated in a variety of tumor cells, regulates the folding, stability and degradation of many oncogenic signaling proteins.
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)c1cc(C(=O)N2Cc3ccc(CN4CCN(C)CC4)cc3C2)c(O)cc1O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200