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ProductsBack/ONC206

ONC206

ORB1089600

CAS Number1638178-87-6

Product group Chemicals

Molecular Weight408.4437919

Overview

Supplier
Biorbyt
Product Name
ONC206 [1638178-87-6]
Delivery Days Customer
10
CAS Number
1638178-87-6
Certification
Research Use Only
Molecular Formula
C23H22F2N4O
Molecular Weight
408.4437919
Scientific Description
ONC206 is a chemical analogue of ONC201. ONC206 is a benzyl-flurobenzyl imipridone that has highly potent activity in preclinical models of difficult-to-treat neuroendocrine tumors and sarcomas. ONC206 acts as a selective antagonist of DRD2 at nanomolar concentrations and has broad-spectrum anti-tumor activity. ONC206 may address tumor types where the properties of ONC201 do not permit for complete therapeutic engagement in vivo.
SMILES
O=C1C2CN(CCC=2N2C(=NCC2)N1CC1C(F)=CC(F)=CC=1)CC1C=CC=CC=1
UNSPSC
12352200

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