Oncrasin-1

Selleck Chemicals

Oncrasin-1

9

Research Use Only

Oncrasin-1 (Onc-1) is a potent RNA polymerase II inhibitor with antitumor activity that kills various human lung cancer cells with K-Ras mutations. Oncrasin-1 drives abnormal aggregation of protein kinase C iota (PKCjota) in nucleus of sensitive cells but not in resistant cells.

12352200