Ononin [486-62-4]

Chemodex

Ononin [486-62-4]

10

486-62-4

Research Use Only

>98%

C22H22O9

430.4

Chemical. CAS: 486-62-4. Formula: C22H22O9. MW: 430.40. Ononin is a glycoside isoflavone that has been found in soybeans. It has anti-inflammatory activity by inhibiting the NF-kappaB and MAPK pathways and neuroprotective properties. Ononin inhibits LPS-induced production of nitrite, prostaglandin E2 and the pro-inflammatory cytokines IL-1beta, IL-6, and TNF-alpha by RAW 264.7 macrophages. It also inhibits glutamate-induced toxicity in rat adrenal PC12 cells. - Ononin is a glycoside isoflavone that has been found in soybeans. It has anti-inflammatory activity by inhibiting the NF-kappaB and MAPK pathways and neuroprotective properties. Ononin inhibits LPS-induced production of nitrite, prostaglandin E2 and the pro-inflammatory cytokines IL-1beta, IL-6, and TNF-alpha by RAW 264.7 macrophages. It also inhibits glutamate-induced toxicity in rat adrenal PC12 cells.

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RT

12352200