ONX-0914
M2071
CAS Number960374-59-8
Product group Chemicals
Estimated Purity>99%
Molecular Weight580.67
Overview
- SupplierAbMole BioScience
- Product NameONX-0914
- Delivery Days Customer9
- CAS Number960374-59-8
- CertificationResearch Use Only
- Estimated Purity>99%
- Molecular FormulaC31H40N4O7
- Molecular Weight580.67
- Scientific DescriptionOnx-0914 (PR-957) is a selective inhibitor of low molecular weight polypeptide 7 (LMP7), a chymotrypsin subunit of the immune proteasome. Onx-0914 blocks cytokine production and reduces the progression of experimental arthritis. Onx-0914 is a non-competitive irreversible inhibitor of mycobacterium proteasome (Ki=5.2 uM). Onx-0914 activates latent HIV-1 through HF-1-mediated p-TEFb activation.
- SMILESL-Tyrosinamide, N-[2-(4-morpholinyl)acetyl]-L-alanyl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-
- UNSPSC12352200
Datasheet
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