Ophiopogonin-D
M4131
CAS Number945619-74-9
Product group Chemicals
Molecular Weight855.02
Overview
- SupplierAbMole BioScience
- Product NameOphiopogonin-D
- Delivery Days Customer9
- CAS Number945619-74-9
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC44H70O16
- Molecular Weight855.02
- Scientific DescriptionOphiopogonin D, isolated from the tuber of Ophiopogon japonicus, is a rare naturally occurring C29 steroid glycoside. Ophiopogonin D is a CYP2J3 inducer. By increasing the expression of CYP2J2/EETs and PPARalfa in human umbilical vein endothelial cells (HUVECs), Ophiopogonin D significantly inhibited Ang Ii-induced NF-kappaB nuclear translocation and IkappaBalfa down-regulation. Intracellular Ca2+ overload and activation of pro-inflammatory cytokines.
- SMILESCC1CCC2(OC1)OC3CC4C5CC=C6CC(O)CC(OC7OC(C)C(O)C(OC8OCC(O)C(O)C8O)C7OC9OC(C)C(O)C(O)C9O)C6(C)C5CCC4(C)C3C2C
- Storage Instruction4°C, protect from light, dry, sealed
- UNSPSC12352200