Opiranserin (hydrochloride) [1440796-75-7]

MedChem Express

Opiranserin (hydrochloride) [1440796-75-7]

10

1440796-75-7

Research Use Only

99.62

C21H35ClN2O5

430.97

Opiranserin (VVZ-149) hydrochloride, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 microM, respectively. Opiranserin hydrochloride shows antagonistic activity on rP2X3 (IC50=0.87 microM). Opiranserin hydrochloride is development as an injectable agent for the treatment of postoperative pain[1][2][3].

O=C(C1=CC(OC)=C(OCCCC)C(OC)=C1)NCC2(CCOCC2)N(C)C.[H]Cl

2°C to 8°C

12352200