Oprozomib

MedChem Express

Oprozomib [935888-69-0]

10

935888-69-0

Research Use Only

99.76

C25H32N4O7S

532.61

Oprozomib (PR-047) is an orally bioavailable and selective peptide epoxyketone proteasome inhibitor with IC50s of 36 and 82 nM for proteasome (beta5) and immunoproteasome (LMP7), respectively. Oprozomib (ONX 0912) induces apoptosis in MM cells[1].

C[C@]1(OC1)C([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC(C3=CN=C(C)S3)=O)COC)=O)COC)=O)=O

-20°C,2°C to 8°C

12352200