ORC6 antibody [3A4]

GeneTex

ORC6 antibody [3A4]

9

Recommended Starting Dilutions:For WB: Use at 1:1000Optimal dilutions should be determined experimentally by the researcher.

ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation

Research Use Only

Monoclonal

3A4

1 mg/ml

Unconjugated

ORC6

origin recognition complex subunit 6

ORC6L, origin recognition complex subunit 6

Rat

IgG2a

Origin recognition complex subunit 6

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq, Oct 2010]

-20°C or -80°C,2°C to 8°C

12352203