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Orelabrutinib

HY-129390
MedChem Express
CAS Number1655504-04-3
Product group Chemicals
Estimated Purity99.97
Molecular Weight427.50
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Orelabrutinib [1655504-04-3]
  • Delivery Days Customer
    5
  • CAS Number
    1655504-04-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.97
  • Molecular Formula
    C26H25N3O3
  • Molecular Weight
    427.50
  • Scientific Description
    Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Brutons tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. Orelabrutinib prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways, inhibiting the growth of malignant B-cells that overexpress BTK [1] [2] .
  • SMILES
    O=C(C1=CC=C(C2CCN(C(C=C)=O)CC2)N=C1C3=CC=C(OC4=CC=CC=C4)C=C3)N
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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