Orexin receptor antagonist 4 [2251017-69-1]
HY-146517
CAS Number2251017-69-1
Product group Chemicals
Molecular Weight408.47
Overview
- SupplierMedChem Express
- Product NameOrexin receptor antagonist 4 [2251017-69-1]
- Delivery Days Customer10
- CAS Number2251017-69-1
- CertificationResearch Use Only
- Molecular FormulaC23H25FN4O2
- Molecular Weight408.47
- Scientific DescriptionOrexin receptor antagonist 4 is potent and selective orexin 2 receptor (OX2R) antagonist with an IC50 of 4.27 nM. Orexin receptor antagonist 4 is 61-fold selective for the OX2R over the OX1R (IC50 of 295 nM) (WO2018206959A1; example 1)[1].
- SMILES[H][C@@]12CN(C[C@@]1(CN([C@H]2C)C(C3=CC=C(C=C3F)OC)=O)[H])C4=NC(C)=C(C(C)=C4)C#N
- UNSPSC12131703