Org 25543 (hydrochloride) [495076-64-7]

MedChem Express

Org 25543 (hydrochloride) [495076-64-7]

14

495076-64-7

Research Use Only

99.93

C24H33ClN2O4

448.98

Org 25543 hydrochloride is a selective and irreversible GlyT2 inhibitor (IC50: 16 nM). Org 25543 hydrochloride has analgesia effect. Org 25543 hydrochloride ameliorates mechanical allodynia after partial sciatic nerve ligation injury in mice[1][2][3].

COC(C=C(C(NCC1(CCCC1)N(C)C)=O)C=C2OC)=C2OCC3=CC=CC=C3.[H]Cl

-20°C

12352200