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Org 48762-0 [755753-89-0]

HY-114221
MedChem Express
CAS Number755753-89-0
Product group Chemicals
Estimated Purity99.99
Molecular Weight398.41
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Org 48762-0 [755753-89-0]
  • Delivery Days Customer
    5
  • CAS Number
    755753-89-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.99
  • Molecular Formula
    C24H16F2N4
  • Molecular Weight
    398.41
  • Scientific Description
    Org 48762-0 (UR13870) is a potent, orally active and selective p38 inhibitor with an EC50 of 0.1 microM for p38alpha kinase. Org 48762-0 shows a high degree of kinase selectivity for p38alpha and p38beta over other kinases. Org 48762-0 reduces Lipopolysaccharides (HY-D1056) (LPS)-induced TNFalpha release. Org 48762-0 can be used for the study of rheumatoid arthritis (RA) and Werner syndrome[1][2].
  • SMILES
    CN1N=C2C(C(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)C(C5=CC=C(F)C=C5)=N2)=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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