Orotic acid-13C,15N2 (monohydrate)

MedChem Express

Orotic acid-13C,15N2 (monohydrate) [1346602-15-0]

5

1346602-15-0

Research Use Only

99.93

C4 13CH6 15N2O5

177.09

Orotic acid- 13 C, 15 N 2 (monohydrate) is the 13 C and 15 N labeled Orotic acid[1]. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats[2][3][4].

OC(C1=CC([15NH][13C]([15NH]1)=O)=O)=O.O

2°C to 8°C

12352200