Orotic acid [65-86-1]

MedChem Express

Orotic acid [65-86-1]

10

65-86-1

Research Use Only

99.98

C5H4N2O4

156.10

Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats[1][2][3].

O=C(C(NC1=O)=CC(N1)=O)O

-20°C,2°C to 8°C

12352200