OSMI-1 [1681056-61-0]
T16409
CAS Number1681056-61-0
Product group Chemicals
Estimated Purity99.83%
Molecular Weight563.64
Overview
- SupplierTargetMol Chemicals
- Product NameOSMI-1 [1681056-61-0]
- Delivery Days Customer9
- CAS Number1681056-61-0
- CertificationResearch Use Only
- Chemical NameOSMI-1
- Estimated Purity99.83%
- Molecular FormulaC28H25N3O6S2
- Molecular Weight563.64
- Scientific DescriptionOSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 microM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans.
- Shelf life instruction3 years
- SMILESCOc1ccccc1C(NS(=O)(=O)c1ccc2[nH]c(=O)ccc2c1)C(=O)N(Cc1ccco1)Cc1cccs1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Lee KS, Lee J, Lee P, et al. Inhibition of O-GlcNAcylation protects from Shiga toxin-mediated cell injury and lethality in host. EMBO Mol Med. 2022,14(1):e14678. doi: 10.15252/emmm.202114678Read this paper
MSDS
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