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OSMI-1 [1681056-61-0]

OSMI-1 [1681056-61-0]

T16409
TargetMol Chemicals
CAS Number1681056-61-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.83%
Molecular Weight563.64
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    OSMI-1 [1681056-61-0]
  • Delivery Days Customer
    9
  • CAS Number
    1681056-61-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    OSMI-1
  • Estimated Purity
    99.83%
  • Molecular Formula
    C28H25N3O6S2
  • Molecular Weight
    563.64
  • Scientific Description
    OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 microM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans.
  • Shelf life instruction
    3 years
  • SMILES
    COc1ccccc1C(NS(=O)(=O)c1ccc2[nH]c(=O)ccc2c1)C(=O)N(Cc1ccco1)Cc1cccs1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Inhibition of O-GlcNAcylation protects from Shiga toxin-mediated cell injury and lethality in host. Lee KS et al., 2022 Jan 11, EMBO Mol Med
    Read more

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