Osoresnontrine [1189767-28-9]

MedChem Express

Osoresnontrine [1189767-28-9]

10

1189767-28-9

Research Use Only

99.88

C16H17N5O2

311.34

Osoresnontrine (BI-409306) is a potent and selective PDE9A inhibitor, with an IC50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A (IC50, 1.4 microM), PDE1C (IC50, 1.0 microM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 all > 10 microM); Osoresnontrine can be used in the research of memory enhancement in CNS disorders.

O=C1C2=C(N(C3CCOCC3)N=C2)NC(CC4=CC=CC=N4)=N1

-20°C,2°C to 8°C

12352200