OSS_128167

MedChem Express

OSS_128167 [887686-02-4]

9

887686-02-4

Research Use Only

98.63

C19H14N2O6

366.32

OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 microM, 1578 microM and 751 microM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects[1][2].

O=C(C1=CC(NC(C2=CC=CO2)=O)=CC=C1)NC3=CC(C(O)=O)=C(O)C=C3

-20°C,2°C to 8°C

12352200