Osteopontin/OPN, Human (HEK293, His)
HY-P70499
Protein IDP10451
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameOsteopontin/OPN, Human (HEK293, His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity98.00
- Gene ID6696
- Target nameSPP1
- Target descriptionsecreted phosphoprotein 1
- Target synonymsBNSP, BSPI, ETA-1, OPN, osteopontin, SPP1/CALPHA1 fusion, early T-lymphocyte activation 1, lnc-PKD2-2-3, nephropontin, osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein, secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1), urinary stone protein, uropontin
- Protein IDP10451
- Protein NameOsteopontin
- Scientific DescriptionOsteopontin/OPN is a secretory glycophosphoprotein belonging to the SIBLING family. It contains RGD sequences and phosphorylation sites and can bind to integrins alphavbeta3, alpha4beta1 and CD44 receptors. Osteopontin/OPN regulates cell adhesion and migration through receptor-mediated regulation, activates MAPK/ERK and PI3K-AKT to promote tumor invasion, and upregulates TIMP-1/2 to inhibit MMPs and protect cartilage. Osteopontin/OPN can be used in the study of osteoarthritis, liver cancer, etc[1][2][3].
- Storage InstructionStored at -20°C for 2 years
- UNSPSC12352202
- SpeciesHuman