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OSU-T315

HY-18676
MedChem Express
CAS Number2070015-22-2
DownloadMSDS
Product group Chemicals
Estimated Purity99.88
Molecular Weight533.59
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Overview

  • Supplier
    MedChem Express
  • Product Name
    OSU-T315 [2070015-22-2]
  • Delivery Days Customer
    10
  • CAS Number
    2070015-22-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.88
  • Molecular Formula
    C30H30F3N5O
  • Molecular Weight
    533.59
  • Scientific Description
    OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC 50 of 0.6 microM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3beta and myosin light chain) [1] . OSU-T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase-dependent apoptosis in an ILK-independent manner [2] . OSU-T315 causes cell death through apoptosis and autophagy [1] .
  • SMILES
    O=C(NC)CCC1=CC(C2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)=NN1C4=CC=C(N5CCNCC5)C=C4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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