OTS186935 (hydrochloride)

MedChem Express

OTS186935 (hydrochloride)

5

Research Use Only

99.22

C25H26ClN5O2.8/5HCl

522.31

OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC 50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochloride regulates the production of gamma-H2AX in cancer cells [1] .

COC1=C(Cl)C=C(C2=CN3C=CC(N4C[C@@H](NCC5=CC=NC=C5)CC4)=CC3=N2)C(OC)=C1.[H]Cl.[8/5]

2°C to 8°C

12352200