OTS964 [1338542-14-5]

MedChem Express

OTS964 [1338542-14-5]

10

1338542-14-5

Research Use Only

C23H24N2O2S

392.51

OTS964 is an orally active, high affinity and selective TOPK inhibitor with an IC50 of 28 nM[1]. OTS964 is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM[2].

O=C(N1)C2=C(C=CS2)C3=C1C(C)=CC(O)=C3C4=CC=C([C@@H](C)CN(C)C)C=C4

12352200