OTUD5, Human (His, FLAG)

MedChem Express

OTUD5, Human (His, FLAG)

14

Research Use Only

94.00

OTUD5

OTU deubiquitinase 5

DUBA, MCAND, OTU domain-containing protein 5, OTU domain containing 5, deubiquinating enzyme A, deubiquitinase A, deubiquitinating enzyme A

OTU domain-containing protein 5

The OTUD5 protein is a deubiquitinating enzyme that crucially eliminates the innate immune response through peptidase activity on Lys-48 and Lys-63 linked polyubiquitin chains, thereby inhibiting TRAF3-mediated Type I interferon production. It acts as a regulator of neuroectodermal differentiation by cleaving Lys-48 linked ubiquitin chains to prevent the degradation of chromatin regulators such as ARID1A, HDAC2 and HCF1. OTUD5 Protein, Human (His, FLAG) is the recombinant human-derived OTUD5 protein, expressed by E. coli , with N-6*His, N-Flag labeled tag.

-80°C

41116100

Human