OTUD7B, Human (sf9, His, StreII)

MedChem Express

OTUD7B, Human (sf9, His, StreII)

14

Research Use Only

90.00

OTUD7B

OTU deubiquitinase 7B

CEZANNE, ZA20D1, OTU domain-containing protein 7B, OTU domain containing 7B, cellular zinc finger anti-NF-kappa-B protein, cellular zinc finger anti-NF-kappaB Cezanne, zinc finger A20 domain-containing protein 1, zinc finger protein Cezanne, zinc finger, A20 domain containing 1

OTU domain-containing protein 7B

The OTUD7B protein acts as a negative regulator to inhibit the non-canonical NF-kappa-B pathway by deubiquitinating TRAF3, thereby inhibiting B cell responses. It prevents degradation of Lys-48-linked polyubiquitin chains on TRAF3 during atypical NF-kappa-B stimulation, avoiding overactivation of the pathway and affecting mucosal immunity. OTUD7B Protein, Human (sf9, His, Strep) is the recombinant human-derived OTUD7B protein, expressed by sf9 insect cells , with N-Strep, N-8*His labeled tag.

-80°C

41116100