OX40 Ligand/TNFSF4, Cynomolgus (HEK293, His)

MedChem Express

OX40 Ligand/TNFSF4, Cynomolgus (HEK293, His)

10

Research Use Only

96.03

TNFSF4

TNF superfamily member 4

EGK_01976, TNLG2B, tumor necrosis factor ligand superfamily member 4, tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa), tumor necrosis factor ligand 2B, tumor necrosis factor superfamily member 4

Tumor necrosis factor ligand 2B

OX40 Ligand (TNFSF4) is a type II glycoprotein with a cytoplasmic tail of 23 aa and an extracellular domain of 133 aa[1]. OX40 Ligand is a ligand for TNFRSF4 (CD134), belongs to tumor necrosis factor (TNF) family. OX40 Ligand can activate OX40 and thereby functioning as a T cell co-stimulatory molecule. The OX40-OX40 Ligand interaction promotes effector T-cell survival and effectively induces memory T-cell generation, as well as enhances the helper function of Tfh for B cells, and also promotes the differentiation and maturation of DCs[1][2]. OX40 Ligand/TNFSF4 Protein, Cynomolgus (HEK293, His) is a recombinant cynomolgus OX40 Ligand (Q51-L183) with N-terminal 8*His tag, which is produced in HEK293.

-20°C

41116100