OX40 Ligand/TNFSF4, Human (HEK293, Fc)

MedChem Express

OX40 Ligand/TNFSF4, Human (HEK293, Fc)

5

Research Use Only

95.40

TNFSF4

TNF superfamily member 4

CD134 ligand; CD134L; CD252; glycoprotein Gp34; GP34; OX40 antigen ligand; OX-40L; OX4OL; tax-transcriptionally activated glycoprotein 1 (34kD); TNLG2B; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor ligand 2B; tumor necrosis factor ligand superfamily member 4; tumor necrosis factor superfamily member 4; TXGP1

Tumor necrosis factor ligand superfamily member 4

OX40 Ligand (TNFSF4) is a type II glycoprotein with a cytoplasmic tail of 23 aa and an extracellular domain of 133 aa[1]. OX40 Ligand is a ligand for TNFRSF4 (CD134), belongs to tumor necrosis factor (TNF) family. OX40 Ligand can activate OX40 and thereby functioning as a T cell co-stimulatory molecule. The OX40-OX40 Ligand interaction promotes effector T-cell survival and effectively induces memory T-cell generation, as well as enhances the helper function of Tfh for B cells, and also promotes the differentiation and maturation of DCs[1][2]. OX40 Ligand/TNFSF4 Protein, Human (HEK293, Fc) is a recombinant human OX40 Ligand (Q51-L183) with N-terminal hFc tag, which is produced in HEK293.

-80°C

41116100